Enhance Genomic Research with Polygenic Risk Score Calculations in SVS

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About this webinar

December 20th, 2023 // 12:00 PM EST

Presented By: Gabe Rudy, VP of Product & Engineering

Golden Helix’s SNP & Variation Suite (SVS) has been used by researchers around the world to do trait analysis and association testing on large cohorts of samples in both humans and other species. The latest SVS release introduces a significant leap in capabilities, with a focus on advanced Polygenic Risk Score (PRS) calculations. PRS has become a fundamental tool in genomic research, enabling the identification of correlations between genotypic variants and phenotypes across large populations.

This enhancement is particularly relevant for researchers working on large cohorts and meta-analysis. Please watch us as we explore:
  • SVS Workflow Review: A review of the extensive capabilities of SVS to meaningful insights from large cohorts and association test result datasets
  • Computing Polygenic Risk Scores: An overview of the PRS capabilities in SVS, including Clumping and Thresholding and creation of multiple PRS models
  • Evaluating and Applying PRS: Evaluating PRS models in-sample and out-of-sample and applying PRS models to perform trait prediction
  • Future Implications: Brief exploration of how these advancements in SVS could influence future genomic research.

    • This webcast explores how SVS facilitates the creation of multiple PRS models from large-scale genomic data, such as those obtained from extensive cohort studies or comprehensive meta-analyses. Watch to discover how these latest updates in SVS are supporting large-scale genomic research.

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