From FASTQ to Clinical Report

We provide a complete, end-to-end solution for clinical labs and hospitals to analyze Next-Generation Sequencing data.


In business for 20 years and cited in 1,300+ publications, we are proud to support over 10,000 users in more than 400 institutions worldwide.


Our entire clinical pipeline consists of software products that are deeply integrated with each other. In addition, we provide automation capabilities that are crucial in high-throughput testing environments.


No per-sample charges! You will save money with our annual subscription model. Licenses include unlimited training and support to ensure success.

Popular Products

SNP & Variation Suite

SNP & Variation Suite is a powerful analytic tool that allows biologists and other researchers to easily perform complex analyses and visualizations on genomic and phenotypic data.

  • GWAS & SNP Analysis
  • Large-N DNA-Seq Analysis
  • Genomic Prediction
  • Copy Number Analysis
  • RNA-Seq Analysis

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VarSeq is an intuitive, integrated software solution for tertiary analysis. With VarSeq you can automate your workflows and analyze variants for gene panels, exomes and whole genomes.

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Built on the same algorithms of Varseq, VSWarehouse is a scalable, multi-project warehouse for NGS variant call sets, clinical reports and catalogs of variant assessments.

  • Fully Integrated with VarSeq Workflows
  • Scalable Technology
  • Organize Samples into Projects
  • Centralized Clinical Report Hosting
  • Create Variant Assessment Catalogs

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Support for Various Industries

Customer Testimonials

Jeffrey Rosefeld, Ph.D

Rutgers Cancer Institute of New Jersey

Dr. Jeffrey Rosenfeld, Bioinformatics Scientist

“Being an informatics person, my job is to set the system up. Now that it’s up and running the molecular pathologist can run the samples. They do not need an informatics person to run every sample.”

Read Rosenfeld's Case Study

Benjamin Darbo, Ph.D

University of Iowa

Dr. Benjamin Darbro, Director of Shivanand R. Patil Cytogenetics and Molecular Laboratory

“VarSeq had everything we were looking for with regards to annotation, filtering sources and an actual visual browser within the software itself. But what really set it apart in retrospect is how intuitive it is.”

Read Darbro's Case Study

Heather Huson, Ph.D

Cornell University

Dr. Heather Huson, Professor of Dairy Cattle Genetics, Odyssey DNA Lab

"The huge benefit of SVS is it's user-friendly and you can basically visualize your results in the same program. You don't have to spend nearly as much time manipulating data and results to get it in the right input and output formats."

Read Huson's Case Study

Hela Azaiez, Ph.D

University of Iowa

Dr. Hela Azaiez, Associate Research Scientist, Molecular Otolaryngology and Renal Research Laboratories

“SVS opened so many doors for my research. It allowed me to explore new ideas. It allowed me to do stuff I never thought was even possible to do in that amount of time, so I could test so many hypotheses. All that I had to do is click a button.”

Read Azaiez's Case Study

Rick Kittles, Ph.D

University of Arizona

Dr. Rick Kittles, Director, Center for Population Genetics

"SVS goes beyond simple genotype associations with Identity By Descent (IBD) calculations, principal component analysis, and the ability to visualize results, all in one application. So when people say 'It costs money,' I say it's better to have one program that can do everything than to look for updates on multiple applications all the time."

Read Kittle's Case Study

Recent Webcast

Updates to VSClinical ACMG Guidelines & a Tour of Cancer Annotation Sources

November 7, 2018 | 12:00 PM EST

Presented by: Gabe Rudy, VP of Product & Engineering, Golden Helix

Earlier this year we launched our latest product VSClinical featuring workflow support for the ACMG guidelines with advanced automation capabilities and per-criteria recommendations. It has been amazing to watch the adoption of this product in labs doing both germline and in some cases cancer variant interpretation. Our latest VarSeq 2.1 release demonstrates our approach to iterative product improvements based on our engaged relationship with our customers and includes numerous improvements to VSClinical.

In this webcast, we will cover the new and updated capabilities that can add value to your genetic testing workflows as well as review the VarSeq workflow support somatic variant interpretation in tumors by leveraging our cancer-specific annotations sources. In this webcast, we will:

  • Demonstrate the new “Consortium Classification” support in VSClinical to have an additional ClinVar-like annotation source added to the automated and interactive ACMG scoring process
  • See how previous interpretations are integrated into your VSClinical analysis, whether they are for the current variant or are just in the genomic neighborhood
  • Cover the additional “Lookup in PubMed” variant search feature for finding supporting studies that may provide functional or clinical evidence for a variant
  • See in action the new ACMG Auto Scoring based templates for trio analysis and gene panel tests
  • Review somatic variant filtering and prioritizing in VarSeq and the updates to relevant public annotation sources including CiVIC, ICGC and a new and available to license COSMIC v86!

Whether you have started using VSClinical or would just like to see it in action, this webcast will be one you won’t want to miss. We hope to see you there!