Software System Requirements

General Purpose Hardware Requirements

  • 4GB of RAM
  • Multicore CPU
  • 100GB of space available for annotations and projects

Advanced and Whole Genome Workflow Hardware Requirements

If you are working with whole exomes or genomes, especially for hundreds to thousands of samples, we suggest a high-memory configuration and plenty of storage capacity:

  • 16GB+ of RAM (32GB for Servers)
  • 8+ CPU Cores
  • 1TB of space available for annotations and projects

Operating Systems

Golden Helix VarSeq and SVS are cross-platform natively compiled applications.

The following operating systems are supported:

  • 64-bit Windows 7 or later (32-bit also supported, but not recommended)
  • Linux Ubuntu 14.04 or later (64-bit only)
  • Linux RHEL 6 or later, or equivalently CentOS 6 or later (64-bit only)
  • Mac OS X 10.9 or later

Server Configurations

With a server license, you can install your Golden Helix software solution on a server with multi-user access and shared resources. You can launch any number of instances of the software on the same host, and are only limited by the natural CPU, Memory and Disk resources of the server.

For Windows, you would need to use ability for multi-user Remote Desktop only available on Windows Server. We support Windows Server 2008 or newer.

On Linux, clients can log in from any operating system using SSH and open the Golden Helix software using X11-tunneling to interact with the software. On windows, we suggest a solution like MobaXterm that provides a all-in-one SSH client and X11 server to enable easy logging in, file transfer and opening of remote GUI applications.

Proxy Settings, Firewalls and AntiVirus

To license the software and access public data resources, Golden Helix VarSeq and SVS must be able to access the internet. Limited support for “air-gapped” and offline installations is supported. Please contact our support team for details

Golden Helix VarSeq and SVS can be configured to access the internet through a SOCKS5 or HTTP/HTTPS Tunneling Proxy. Go to Tools -> Proxy Settings… to configure.

The software only needs to make outgoing connections on standard HTTP/HTTPS ports and protocols. If a local firewall is installed that prevents these types of outgoing connections (this is very uncommon), firewall rules will need to be created to whitelist the software.

Note we have run into numerous issues where aggressive anti-virus programs prevent the product from performing normal operations such as opening files and logging in. You may need to whitelist Golden Helix executables or disable these tools to perform your analytics.