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Harvard University Grants Golden Helix, Inc. Exclusive License to PBAT


Bozeman, MT (August 17 , 2006)
- Golden Helix, Inc. announced today that it has been granted exclusive world-wide, royalty-bearing licensing rights to PBAT, a statistical software program that contains tools for the design and analysis of family-based association studies. PBAT implements methods developed by Christoph Lange, PhD, and Nan Laird, PhD, of the Harvard School of Public Health.

The license granted to Golden Helix by Harvard University includes the right to use, copy and make improvements to the software as well as the right to sell licenses for commercial and non-profit research. The program offers an innovative two-step method of identifying and testing the most promising genes that may contribute to chronic and common diseases.

“This is a great opportunity for me and the genetic research community,” said PBAT’s developer, Christoph Lange, PhD. of the Harvard School of Public Health. “Working with Golden Helix will ensure PBAT’s continued success while enabling me to focus on developing needed new methods for the advancement of genetic association studies.”

PBAT has historically been available from Dr. Lange’s web site as a command line program. In accordance with the agreement, Golden Helix has made available a version with a graphical user-interface. This new version can be integrated with Golden Helix’s proprietary HelixTree® Genetics Analysis Software or used as a stand-alone application.

“Golden Helix is committed to supporting a vibrant PBAT community,” stated Christophe Lambert, PhD., President and CEO of Golden Helix. “We will offer personal and timely support, make PBAT easier to use, and improve its functionality, thus enabling more researchers to benefit from its use and power in their studies.”

The agreement also benefits Golden Helix’s existing customers. “Until now we have not been able to provide our customers with a good solution for family-based analysis,” said Josh Forsythe, Director of Marketing at Golden Helix. “The integration of PBAT with HelixTree makes our offering more complete. Our customers will now have access to the best statistical methods available for both population and family-based association studies in a single, easy to use package.”

Financial and other terms of the agreement were not disclosed.

About PBAT
PBAT is a comprehensive software package developed by Christoph Lange of the Harvard School of Public Health that contains tools that help with the design and analysis of a large variety of family-based association studies. Among these tools are power calculations that assess the power of family-based association tests (FBATs) and screening methodologies that help address the multiple-comparison problem in whole-genome association studies. The power of PBAT was confirmed recently in a whole-genome study where it was used to identify the first common genetic variant linked to obesity. It is noteworthy that the study’s findings (published in the April 14, 2006 edition of Science), were replicated in at least a half dozen other studies. For more information about PBAT please visit: http://www.goldenhelix.com/SNP_Variation/PBAT/index.html

About Golden Helix, Inc.
Founded in 1998 in Bozeman, MT, Golden Helix is a leading provider of data analysis software products and services designed to accelerate life science research and increase pharmaceutical R&D productivity. The company's products enable hundreds of researchers at the world's top pharmaceutical, biotech and non-profit research organizations to discover the genes that cause disease, improve target and lead discovery processes, and advance pharmacogenetic initiatives. Its products have been cited in nearly 100 peer reviewed publications that detail ground-breaking research for discovering the genetic and environmental basis of disease and creating safer and more effective medicines.
Golden Helix is committed to Accelerating the Quest for Significance.
For more information, please visit www.goldenhelix.com.

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Media Contact:
Josh Forsythe
Director of Marketing
Golden Helix, Inc.
406-585-8137 x202
jlforsythe[at]goldenhelix.com

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