Golden Helix Newsletter

 
Precision Medicine
Top 5 things you need to know about VSPipeline
by Andreas Scherer,
President & CEO


Recently, Golden Helix, Inc. announced the addition of VSPipeline to our VarSeq software suite. VSPipeline is a command-line interface that will allow high throughput environments the ability to tap the full power of VarSeq's algorithms and flexible project template system from any command line context, including existing bioinformatics pipeline.

So, what is the big deal? Here are the top five most important aspects of this new product.
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Summer Savings
Special Summer Savings!

For many of us, summer is a time relax and take a well deserved break from the hustle and bustle of the year. The summer lull also presents a great time to get to the things you have been putting off all year.

For those of you spending some time this summer tackling your to do list, we offer you the best prices of the year on SVS, VarSeq and VSPipeline! Simply follow the link below to request your quote.
Request Pricing! »

Bioinformatics
Partnership with MedGenome
by Andreas Scherer,
President & CEO


Just a few weeks ago we announced our partnership with MedGenome. The news was covered by a number of outlets including Financial Express and Pharmabiz.

Let me expIain the importance and impact of this announcement.Since Varseq was released, we have received strong interest from testing labs that are leveraging our product to implement cancer diagnostic pipelines. Please feel free to take a look at my e-Book, Genetic Testing for Cancer, on this subject. Now, at Golden Helix we specialize in state of the art filtering and annotation capabilities. Our product ships with annotation sources such as COSMIC, which is a terrific first baseline.
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New and Updated Annotation Tracks Now Available!
by Jami Bartole,
Technical Support Representative


In recent months we have been updating our public annotation library to include the most recent versions of existing sources as well as include new sources. Each of these annotation sources are compatible with our three major products (SVS, GenomeBrowse and VarSeq) and can be used for visualization, annotation and filtering.
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Meta-Analysis
Comparing Variants using a Venn Diagram
by Ashley Hintz,
Field Application Scientist


One of the lesser known functions in SVS allows the user to create Venn diagrams comparing variants found in multiple spreadsheets. These different spreadsheets could come from individuals samples, a case vs. control group or several variant databases. It is a helpful tool for visually comparing different variants.

Start by creating spreadsheets for each group/samples you'd like to compare. The first example here is for a rare variant case/control study. The whole dataset is split into two spreadsheets, one for cases and another controls. This can be easily accomplished by right-clicking on the C/C column and selecting Activate by Category, then choose one category and click OK.
Continue reading »

Using GWAS to Improve the Economics of the Aquaculture Industry
by Cheryl Rogers,
Director of Marketing


Recently, customer Xin Geng of Auburn University published a paper using SVS, and we wanted to share his story with you.

For PhD graduate student Xin Geng, conducting Genome Wide Association Study (GWAS) to uncover the quantitative trait loci (QTL) controlling disease resistance in catfish was not just an interesting study, but potentially the start of finding a way to improve the economics of the aquaculture industry in the United Sates and China.
Continue reading »
 
   CEO Corner
Andreas Scherer
The last month at Golden Helix has been filled with excitement as we launched our latest product, VSPipeline. Essentially we provide the full power of VarSeq in command line form. This is a breakthrough tool for our testing lab clients, which my recent blog explains in further detail. The customer response has been excellent. Fulgent Diagnostics recently adopted VSPipeline and is currently working on integration; see the press release for more information. It's one more step in enabling precision medicine.


   Latest Webcast
Genomic Analysis for Palatability of Beef
Dr. Raluca Mateescu does research in the area of beef cattle, sheep and goat molecular genetics. Most biological traits of economic importance in domestic animals have a complex inheritance (are influenced by many genes and the environment) and the long-term research goal is to unravel the genetic basis for the phenotypic variability in this type of trait. Her research uses recent advances in the animal genomics field with the goal of improving animal production efficiency and enhancing animal products for improved human health.

In this webinar Dr. Mateescu will focus on use of SVS program to perform genome-wide association studies for individual traits describing beef palatability, identify chromosomal regions associated with these traits, estimate genomic breeding values and predict the accuracy of GEBV for palatability traits in beef.

View recording »


   Customer Success


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About Golden Helix
Golden Helix has been delivering industry leading bioinformatics solutions for the advancement of life science research and clinical and translational medicine for over 16 years. Our innovative technologies and analytic services empower scientists and healthcare professionals at all levels to derive meaning from the rapidly increasing volumes of genomic data produced from microarrays and next-generation sequencing. With our solutions, hundreds of the world's top pharmaceutical, clinical laboratories, biotech, and academic research organizations are able to harness the full potential of genomics to identify the cause of disease, improve the efficacy and safety of drugs, develop genomic diagnostics, and advance the quest for precision medicine. Golden Helix products and services have been cited in over 900 peer-reviewed publications.