DNA Variant Analysis of Complete Genomics' Next-Generation Sequencing Data
by Gabe Rudy, VP of Product Development
As I've mentioned in previous blog posts, one of the great aspects of our scientific community is the sharing of public data. With a mission of providing powerful and accurate tools to researchers, we at at Golden Helix especially appreciate the value of having rich and extensive public data to test and calibrate those tools. Public data allow us to do everything from testing the limits of our spreadsheet interface by importing whole genome samples from the 1000 Genomes project, to providing real-world data for incoming users to try full-feature examples of analysis workflows.
In our latest blog post, we examine the richness of Complete Genomics' public samples available from their website. I will lead you through a series of filtering routines to reduce the search space from millions of variants to something more manageable (2,500 variants), all while discussing interesting characteristics of the dataset, perhaps giving you ideas for exploring your next sequence project. Continue reading »
Hands-on Workshop: GWAS & Rare Variant Analysis Using SNP & Variation Suite
Presenter: Dr. Bryce Christensen, Statistical Geneticist
Date: August 24, 9 am - 1 pm | Location: USC, California
Wed, Aug 24th
9 am - 1 pm
Join us next Wednesday for a half-day workshop exploring GWAS and rare variant analysis at University of Southern California.
Register by emailing us »
Please Help Me Get My Regression Model Set Up!
by Greta Linse Peterson, Scientific Quality Analyst
SNP & Variation Suite has a Regression Module to enable researchers with varying degrees of statistical knowledge to interrogate their data using regression models to account for potential confounding effects of covariates and interaction terms. While these tools are labeled "basic", they can be difficult to use and results hard to interpret for those who have only had a course or two in regression analysis.
Continue reading »